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Splice site m(6)A methylation prevents binding of DGCR8 to suppress KRT4 pre-mRNA splicing in oral squamous cell carcinoma

Oral squamous cell carcinoma (OSCC) is the 11th most prevalent tumor worldwide. Despite advantages of therapeutic approaches, the 5-year survival rate of patients with OSCC is less than 50%. It is urgent to elucidate mechanisms underlying OSCC progression for developing novel treatment strategies. O...

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Detalles Bibliográficos
Autores principales: Li, Xiaoxu, Fang, Juan, Tao, Xiaoan, Xia, Juan, Cheng, Bin, Wang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939020/
https://www.ncbi.nlm.nih.gov/pubmed/36811004
http://dx.doi.org/10.7717/peerj.14824