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Asciminib vs bosutinib in CML patients pretreated with ≥2 tyrosine kinase inhibitors: Results from the Japanese subgroup analysis of ASCEMBL study

Asciminib, a first‐in‐class, allosteric inhibitor of BCR‐ABL1 that acts by STAMP (Specifically Targeting the ABL Myristoyl Pocket), is a novel therapeutic option for patients with chronic myeloid leukemia (CML). In the global, phase 3, open‐label ASCEMBL study in patients with CML in chronic phase (...

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Detalles Bibliográficos
Autores principales: Yuda, Junichiro, Doki, Noriko, Matsuoka, Hiroshi, Yokota, Takafumi, Tomita, Akihiro, Takahashi, Naoto, Matsumura, Itaru, Kubo, Kohmei, Goto, Tatsunori, Kirito, Keita, Maki, Akio, Aoki, Makoto, Allepuz, Alex, Minami, Yosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939084/
https://www.ncbi.nlm.nih.gov/pubmed/36168187
http://dx.doi.org/10.1002/cam4.5212