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Breast cancer in East Africa: Prevalence and spectrum of germline SNV/indel and CNVs in BRCA1 and BRCA2 genes among breast cancer patients in Tanzania

BACKGROUND: Growing prevalence and aggressiveness of breast cancer (BC) among East African women strongly indicate that the genetic risk factor implicated in the etiology of the disease may have a key role. Germline pathogenic variants in BRCA1 and BRCA2 (BRCA1/2) are known to increase the lifetime...

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Detalles Bibliográficos
Autores principales: Rweyemamu, Linus P., Gültaşlar, Büşra K., Akan, Gokce, Dharsee, Nazima, Namkinga, Lucy A., Lyantagaye, Sylvester L., Yazıcı, Hülya, Atalar, Fatmahan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939169/
https://www.ncbi.nlm.nih.gov/pubmed/35908255
http://dx.doi.org/10.1002/cam4.5091