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Structural mechanism of a dual-functional enzyme DgpA/B/C as both a C-glycoside cleaving enzyme and an O- to C-glycoside isomerase

The C-glycosidic bond that connects the sugar moiety with aglycone is difficult to be broken or made due to its inert nature. The knowledge of C-glycoside breakdown and synthesis is very limited. Recently, the enzyme DgpA/B/C cascade from a human intestinal bacterium PUE was identified to specifical...

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Detalles Bibliográficos
Autores principales: He, Pengfei, Wang, Sha, Li, Sen, Liu, Siqi, Zhou, Shuqi, Wang, Jing, Tao, Jiayue, Wang, Dongdong, Wang, Rufeng, Ma, Wenfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939296/
https://www.ncbi.nlm.nih.gov/pubmed/36815035
http://dx.doi.org/10.1016/j.apsb.2022.05.022