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Actively separated microneedle patch for sustained-release of growth hormone to treat growth hormone deficiency

Growth hormone deficiency (GHD) has become a serious healthcare burden, and presents a huge impact on the physical and mental health of patients. Here, we developed an actively separated microneedle patch (PAA/NaHCO(3)-Silk MN) based on silk protein for sustained release of recombinant human growth...

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Detalles Bibliográficos
Autores principales: Yang, Li, Liu, Qingyun, Wang, Xinhui, Gao, Nansha, Li, Xiuzhen, Chen, Hongzhong, Mei, Lin, Zeng, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939297/
https://www.ncbi.nlm.nih.gov/pubmed/36815043
http://dx.doi.org/10.1016/j.apsb.2022.04.015