Fluorine-thiol displacement probes for acetaminophen's hepatotoxicity

Chemicals possessing reactive electrophiles can denature innate proteins leading to undesired toxicity, and the overdose-induced liver injury by drugs containing electrophiles has been one of the major causes of non-approval and withdraw by the US Food and Drug Administration (FDA). Elucidating the...

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Detalles Bibliográficos
Autores principales: Prather, Benjamin L., Ji, Shuyue, Zhao, Yue, Shajan, Femil Joseph, Zhao, Mi, Buuh, Zakey Yusuf, Maloney, Robert, Zhang, Rui, Cohen, Carson, Wang, Rongsheng E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939312/
https://www.ncbi.nlm.nih.gov/pubmed/36815027
http://dx.doi.org/10.1016/j.apsb.2022.08.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939312/
https://www.ncbi.nlm.nih.gov/pubmed/36815027
http://dx.doi.org/10.1016/j.apsb.2022.08.003

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