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Fluorine-thiol displacement probes for acetaminophen's hepatotoxicity
Chemicals possessing reactive electrophiles can denature innate proteins leading to undesired toxicity, and the overdose-induced liver injury by drugs containing electrophiles has been one of the major causes of non-approval and withdraw by the US Food and Drug Administration (FDA). Elucidating the...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939312/ https://www.ncbi.nlm.nih.gov/pubmed/36815027 http://dx.doi.org/10.1016/j.apsb.2022.08.003 |