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CYP1B1-derived epoxides modulate the TRPA1 channel in chronic pain

Pain is often debilitating, and current treatments are neither universally efficacious nor without risks. Transient receptor potential (TRP) ion channels offer alternative targets for pain relief, but little is known about the regulation or identities of endogenous TRP ligands that affect inflammati...

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Detalles Bibliográficos
Autores principales: Sun, Lili, Zhang, Jie, Niu, Changshan, Deering-Rice, Cassandra E., Hughen, Ronald W., Lamb, John G., Rose, Katherine, Chase, Kevin M., Almestica-Roberts, Marysol, Walter, Markel, Schmidt, Eric W., Light, Alan R., Olivera, Baldomero M., Reilly, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939319/
https://www.ncbi.nlm.nih.gov/pubmed/36815047
http://dx.doi.org/10.1016/j.apsb.2022.09.007