Embracing enzyme promiscuity with activity-based compressed biosensing

The development of protease-activatable drugs and diagnostics requires identifying substrates specific to individual proteases. However, this process becomes increasingly difficult as the number of target proteases increases because most substrates are promiscuously cleaved by multiple proteases. We...

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Detalles Bibliográficos
Autores principales: Holt, Brandon Alexander, Lim, Hong Seo, Sivakumar, Anirudh, Phuengkham, Hathaichanok, Su, Melanie, Tuttle, McKenzie, Xu, Yilin, Liakakos, Haley, Qiu, Peng, Kwong, Gabriel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939361/
https://www.ncbi.nlm.nih.gov/pubmed/36814844
http://dx.doi.org/10.1016/j.crmeth.2022.100372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939361/
https://www.ncbi.nlm.nih.gov/pubmed/36814844
http://dx.doi.org/10.1016/j.crmeth.2022.100372

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