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Embracing enzyme promiscuity with activity-based compressed biosensing
The development of protease-activatable drugs and diagnostics requires identifying substrates specific to individual proteases. However, this process becomes increasingly difficult as the number of target proteases increases because most substrates are promiscuously cleaved by multiple proteases. We...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939361/ https://www.ncbi.nlm.nih.gov/pubmed/36814844 http://dx.doi.org/10.1016/j.crmeth.2022.100372 |