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Graph embedding and Gaussian mixture variational autoencoder network for end-to-end analysis of single-cell RNA sequencing data

Single-cell RNA sequencing (scRNA-seq) is a revolutionary technology to determine the precise gene expression of individual cells and identify cell heterogeneity and subpopulations. However, technical limitations of scRNA-seq lead to heterogeneous and sparse data. Here, we present autoCell, a deep-l...

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Detalles Bibliográficos
Autores principales: Xu, Junlin, Xu, Jielin, Meng, Yajie, Lu, Changcheng, Cai, Lijun, Zeng, Xiangxiang, Nussinov, Ruth, Cheng, Feixiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939381/
https://www.ncbi.nlm.nih.gov/pubmed/36814845
http://dx.doi.org/10.1016/j.crmeth.2022.100382