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Identifying key multifunctional components shared by critical cancer and normal liver pathways via SparseGMM

Despite the abundance of multimodal data, suitable statistical models that can improve our understanding of diseases with genetic underpinnings are challenging to develop. Here, we present SparseGMM, a statistical approach for gene regulatory network discovery. SparseGMM uses latent variable modelin...

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Detalles Bibliográficos
Autores principales: Bakr, Shaimaa, Brennan, Kevin, Mukherjee, Pritam, Argemi, Josepmaria, Hernaez, Mikel, Gevaert, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939431/
https://www.ncbi.nlm.nih.gov/pubmed/36814838
http://dx.doi.org/10.1016/j.crmeth.2022.100392