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Network pharmacology, molecular docking, and experimental verification reveal the mechanism of San-Huang decoction in treating acute kidney injury

Background: Cisplatin is an effective anti-tumor drug. However, its usage is constrained by side effects such as nephron toxicity. Cisplatin-induced acute kidney injury (AKI) appears in approximately 20%–30% of cases. Hence, finding an effective protective strategy is necessary. San-Huang decoction...

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Detalles Bibliográficos
Autores principales: Liu, Jiahui, Li, Zhongtang, Lao, Yunlan, Jin, Xiaoming, Wang, Yuzhi, Jiang, Beibei, He, Riming, Yang, Shudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939458/
https://www.ncbi.nlm.nih.gov/pubmed/36814499
http://dx.doi.org/10.3389/fphar.2023.1060464