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Single-cell RNA datasets and bulk RNA datasets analysis demonstrated C1Q+ tumor-associated macrophage as a major and antitumor immune cell population in osteosarcoma

BACKGROUND: Osteosarcoma is the most frequent primary bone tumor with a poor prognosis. Immune infiltration proved to have a strong impact on prognosis. We analyzed single-cell datasets and bulk datasets to confirm the main immune cell populations and their properties in osteosarcoma. METHODS: The e...

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Detalles Bibliográficos
Autores principales: Tu, Jihao, Wang, Duo, Zheng, XiaoTian, Liu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939514/
https://www.ncbi.nlm.nih.gov/pubmed/36814925
http://dx.doi.org/10.3389/fimmu.2023.911368