Selective vulnerability of human-induced pluripotent stem cells to dihydroorotate dehydrogenase inhibition during mesenchymal stem/stromal cell purification

The use of induced mesenchymal stem/stromal cells (iMSCs) derived from human induced pluripotent stem cells (hiPSCs) in regenerative medicine involves the risk of teratoma formation due to hiPSCs contamination in iMSCs. Therefore, eradicating the remaining undifferentiated hiPSCs is crucial for the...

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Detalles Bibliográficos
Autores principales: Al-Akashi, Ziadoon, Zujur, Denise, Kamiya, Daisuke, Kato, Tomohisa, Kondo, Toru, Ikeya, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939518/
https://www.ncbi.nlm.nih.gov/pubmed/36814599
http://dx.doi.org/10.3389/fcell.2023.1089945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939518/
https://www.ncbi.nlm.nih.gov/pubmed/36814599
http://dx.doi.org/10.3389/fcell.2023.1089945

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