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Heterogeneity of PD-L1 expression and CD8 lymphocyte infiltration in metastatic colorectal cancer and their prognostic significance

PURPOSE: In recent years, immune checkpoint inhibitors have become a major therapeutic method for the treatment of metastatic colorectal cancer (mCRC). Growing evidence indicates that tumour-infiltrating lymphocytes (TILs) in the tumour microenvironment are a prerequisite for the effectiveness of PD...

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Detalles Bibliográficos
Autores principales: Xin, Haisong, Zhou, Chaoxi, Wang, Guanglin, Liu, Yan, Zhang, Juan, Liu, Youqiang, Li, Baokun, Zhang, Jianfeng, Su, Mingming, Li, Zhihan, Wang, Guiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939551/
https://www.ncbi.nlm.nih.gov/pubmed/36814622
http://dx.doi.org/10.1016/j.heliyon.2023.e13048