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Pyrolyzed deketene curcumin controls regulatory T cell generation and gastric cancer metabolism cooperate with 2-deoxy-d-glucose

Pyrolyzed deketene curcumin GO-Y022 prevents carcinogenesis in a gastric cancer mouse model. However, it is still less clear if GO-Y022 affects tumor-induced immune suppression. In this study, we found that GO-Y022 inhibited Treg generation in the presence of transforming growth factor beta 1 (TGF-β...

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Detalles Bibliográficos
Autores principales: MaruYama, Takashi, Miyazaki, Hirofumi, Lim, Yun-Ji, Gu, Jian, Ishikawa, Masaki, Yoshida, Taichi, Chen, WanJun, Owada, Yuji, Shibata, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939626/
https://www.ncbi.nlm.nih.gov/pubmed/36814928
http://dx.doi.org/10.3389/fimmu.2023.1049713