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Identification of the molecular characteristics associated with microsatellite status of colorectal cancer patients for the clinical application of immunotherapy

Background: Mismatch repair-proficient (pMMR) microsatellite stability (MSS) in colorectal cancer (CRC) indicates an unfavorable therapeutic response to immunotherapy with immune checkpoint inhibitors (ICIs). However, the molecular characteristics of CRC patients with pMMR MSS remain largely unknown...

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Detalles Bibliográficos
Autores principales: Fu, Jie, Jin, Xiaoxin, Chen, Weidong, Chen, Zongyao, Wu, Peidong, Xiao, Wang, Liu, Yuhang, Deng, Shuangya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939640/
https://www.ncbi.nlm.nih.gov/pubmed/36814498
http://dx.doi.org/10.3389/fphar.2023.1083449