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Sustained-release losartan from peptide nanofibers promotes chondrogenesis

Introduction: The central pathologic feature of osteoarthritis (OA) is the progressive loss of articular cartilage, which has a limited regenerative capacity. The TGF-β1 inhibitor, losartan, can improve cartilage repair by promoting hyaline rather that fibrous cartilage tissue regeneration. However,...

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Detalles Bibliográficos
Autores principales: Yamaura, Kohei, Sather, Nicholas A., Metlushko, Anna, Nishimura, Haruki, Pavlović, Radoslav Z., Hambright, Sealy, Ravuri, Sudheer K., Philippon, Marc J., Stupp, Samuel I., Bahney, Chelsea S., Huard, Johnny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939695/
https://www.ncbi.nlm.nih.gov/pubmed/36814717
http://dx.doi.org/10.3389/fbioe.2023.1122456