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Discovery of a biomarker for β-Thalassemia by HPLC-MS and improvement from Proton Transfer Reaction – Parallel Ion Parking

β-thalassemia is a quantitative hemoglobin (Hb) disorder resulting in reduced production of Hb A and increased levels of Hb A(2). Diagnosis of β-thalassemia can be problematic when combined with other structural Hb variants, so that the separation approaches in routine clinical centers are not suffi...

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Detalles Bibliográficos
Autores principales: Lin, Yuan, Agarwal, Archana M., Anderson, Lissa C., Marshall, Alan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939715/
https://www.ncbi.nlm.nih.gov/pubmed/36814695
http://dx.doi.org/10.1016/j.jmsacl.2023.01.004