IgG2 rules: N-acetyl-β-D-glucosamine-specific IgG2 and Th17/Th1 cooperation may promote the pathogenesis of acute rheumatic heart disease and be a biomarker of the autoimmune sequelae of Streptococcus pyogenes

Antecedent group A streptococcal pharyngitis is a well-established cause of acute rheumatic fever (ARF) where rheumatic valvular heart disease (RHD) and Sydenham chorea (SC) are major manifestations. In ARF, crossreactive antibodies and T cells respond to streptococcal antigens, group A carbohydrate...

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Detalles Bibliográficos
Autores principales: Kirvan, Christine A., Canini, Heather, Swedo, Susan E., Hill, Harry, Veasy, George, Jankelow, David, Kosanke, Stanley, Ward, Kent, Zhao, Yan D., Alvarez, Kathy, Hedrick, Andria, Cunningham, Madeleine W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939767/
https://www.ncbi.nlm.nih.gov/pubmed/36815140
http://dx.doi.org/10.3389/fcvm.2022.919700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939767/
https://www.ncbi.nlm.nih.gov/pubmed/36815140
http://dx.doi.org/10.3389/fcvm.2022.919700

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