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Head pleomorphic sarcoma showing murine double minute 2 amplification without a well‐differentiated liposarcoma component in a pediatric patient

BACKGROUND: Murine double minute 2 (MDM2) is an oncogene that inhibits p53, leading to decreased apoptosis. Sarcomas showing MDM2 amplification are rare among pediatric patients. CASE: A 14‐year‐old boy presented with pleomorphic sarcoma of the head showing MDM2 amplification without a well‐differen...

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Detalles Bibliográficos
Autores principales: Akaihata, Mitsuko, Takahashi, Ikuko, Kakuda, Yuko, Kawata, Takuya, Mukaigawa, Takashi, Onitsuka, Testuro, Murayama, Shigeyuki, Ishida, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939988/
https://www.ncbi.nlm.nih.gov/pubmed/36572546
http://dx.doi.org/10.1002/cnr2.1774