Amplified therapeutic targets in high-grade serous ovarian carcinoma – a review of the literature with quantitative appraisal

High-grade serous ovarian carcinoma is a unique cancer characterised by universal TP53 mutations and widespread copy number alterations. These copy number alterations include deletion of tumour suppressors and amplification of driver oncogenes. Given their key oncogenic roles, amplified driver genes...

Descripción completa

Detalles Bibliográficos
Autores principales: Talbot, Thomas, Lu, Haonan, Aboagye, Eric O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940086/
https://www.ncbi.nlm.nih.gov/pubmed/36804485
http://dx.doi.org/10.1038/s41417-023-00589-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940086/
https://www.ncbi.nlm.nih.gov/pubmed/36804485
http://dx.doi.org/10.1038/s41417-023-00589-z

Ejemplares similares