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In silico assessment on TdP risks of drug combinations under CiPA paradigm

Researchers have recently proposed the Comprehensive In-vitro Proarrhythmia Assay (CiPA) to analyze medicines’ TdP risks. Using the TdP metric known as qNet, numerous single-drug effects have been studied to classify the medications as low, intermediate, and high-risk. Furthermore, multiple medicati...

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Detalles Bibliográficos
Autores principales: Qauli, Ali Ikhsanul, Marcellinus, Aroli, Setiawan, Muhammad Aldo, Zain, Andi Faiz Naufal, Pinandito, Azka Muhammad, Lim, Ki Moo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940090/
https://www.ncbi.nlm.nih.gov/pubmed/36807374
http://dx.doi.org/10.1038/s41598-023-29208-5