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‘Chemistry at the speed of sound’: automated 1536-well nanoscale synthesis of 16 scaffolds in parallel

Screening of large and diverse libraries is the ‘bread and butter’ in the first phase of the discovery of novel drugs. However, maintenance and periodic renewal of high-quality large compound collections pose considerable logistic, environmental and monetary problems. Here, we exercise an alternativ...

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Detalles Bibliográficos
Autores principales: Gao, Li, Shaabani, Shabnam, Reyes Romero, Atilio, Xu, Ruixue, Ahmadianmoghaddam, Maryam, Dömling, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940305/
https://www.ncbi.nlm.nih.gov/pubmed/36824604
http://dx.doi.org/10.1039/d2gc04312b