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‘Chemistry at the speed of sound’: automated 1536-well nanoscale synthesis of 16 scaffolds in parallel
Screening of large and diverse libraries is the ‘bread and butter’ in the first phase of the discovery of novel drugs. However, maintenance and periodic renewal of high-quality large compound collections pose considerable logistic, environmental and monetary problems. Here, we exercise an alternativ...
Autores principales: | Gao, Li, Shaabani, Shabnam, Reyes Romero, Atilio, Xu, Ruixue, Ahmadianmoghaddam, Maryam, Dömling, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940305/ https://www.ncbi.nlm.nih.gov/pubmed/36824604 http://dx.doi.org/10.1039/d2gc04312b |
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