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Not1 and Not4 inversely determine mRNA solubility that sets the dynamics of co-translational events

BACKGROUND: The Ccr4-Not complex is mostly known as the major eukaryotic deadenylase. However, several studies have uncovered roles of the complex, in particular of the Not subunits, unrelated to deadenylation and relevant for translation. In particular, the existence of Not condensates that regulat...

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Detalles Bibliográficos
Autores principales: Allen, George, Weiss, Benjamin, Panasenko, Olesya O., Huch, Susanne, Villanyi, Zoltan, Albert, Benjamin, Dilg, Daniel, Zagatti, Marina, Schaughency, Paul, Liao, Susan E., Corden, Jeff, Polte, Christine, Shore, David, Ignatova, Zoya, Pelechano, Vicent, Collart, Martine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940351/
https://www.ncbi.nlm.nih.gov/pubmed/36803582
http://dx.doi.org/10.1186/s13059-023-02871-7