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Not1 and Not4 inversely determine mRNA solubility that sets the dynamics of co-translational events
BACKGROUND: The Ccr4-Not complex is mostly known as the major eukaryotic deadenylase. However, several studies have uncovered roles of the complex, in particular of the Not subunits, unrelated to deadenylation and relevant for translation. In particular, the existence of Not condensates that regulat...
Autores principales: | Allen, George, Weiss, Benjamin, Panasenko, Olesya O., Huch, Susanne, Villanyi, Zoltan, Albert, Benjamin, Dilg, Daniel, Zagatti, Marina, Schaughency, Paul, Liao, Susan E., Corden, Jeff, Polte, Christine, Shore, David, Ignatova, Zoya, Pelechano, Vicent, Collart, Martine A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940351/ https://www.ncbi.nlm.nih.gov/pubmed/36803582 http://dx.doi.org/10.1186/s13059-023-02871-7 |
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