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Synthesis, DFT investigations, antioxidant, antibacterial activity and SAR-study of novel thiophene-2-carboxamide derivatives

Synthetic strategy for the synthesis of thiophene 2-carboxamide derivatives substituted with hydroxyl, methyl and amino groups at position-3 was proposed. The strategy includes the cyclization of the precursor ethyl 2-arylazo-3-mercapto-3-(phenylamino)acrylate derivatives, 2-acetyl-2-arylazo-thioace...

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Detalles Bibliográficos
Autores principales: Metwally, Heba M., Khalaf, Norhan A., Abdel-Latif, Ehab, Ismail, Mohamed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940361/
https://www.ncbi.nlm.nih.gov/pubmed/36803621
http://dx.doi.org/10.1186/s13065-023-00917-2