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P2RX7 promotes osteosarcoma progression and glucose metabolism by enhancing c-Myc stabilization

BACKGROUND: Osteosarcoma is the most common malignant tumor in bone and its prognosis has reached a plateau in the past few decades. Recently, metabolic reprogramming has attracted increasing attention in the field of cancer research. In our previous study, P2RX7 has been identified as an oncogene i...

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Detalles Bibliográficos
Autores principales: Sheng, Gaohong, Gao, Yuan, Ding, Qing, Zhang, Ruizhuo, Wang, Tianqi, Jing, Shaoze, Zhao, Hongqi, Ma, Tian, Wu, Hua, Yang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940387/
https://www.ncbi.nlm.nih.gov/pubmed/36803784
http://dx.doi.org/10.1186/s12967-023-03985-z