Impaired neurogenesis and neural progenitor fate choice in a human stem cell model of SETBP1 disorder

BACKGROUND: Disruptions of SETBP1 (SET binding protein 1) on 18q12.3 by heterozygous gene deletion or loss-of-function variants cause SETBP1 disorder. Clinical features are frequently associated with moderate to severe intellectual disability, autistic traits and speech and motor delays. Despite the...

Descripción completa

Detalles Bibliográficos
Autores principales: Cardo, Lucia F., de la Fuente, Daniel C., Li, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940404/
https://www.ncbi.nlm.nih.gov/pubmed/36805818
http://dx.doi.org/10.1186/s13229-023-00540-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940404/
https://www.ncbi.nlm.nih.gov/pubmed/36805818
http://dx.doi.org/10.1186/s13229-023-00540-x

Ejemplares similares