Impaired neurogenesis and neural progenitor fate choice in a human stem cell model of SETBP1 disorder

BACKGROUND: Disruptions of SETBP1 (SET binding protein 1) on 18q12.3 by heterozygous gene deletion or loss-of-function variants cause SETBP1 disorder. Clinical features are frequently associated with moderate to severe intellectual disability, autistic traits and speech and motor delays. Despite the...

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Detalles Bibliográficos
Autores principales: Cardo, Lucia F., de la Fuente, Daniel C., Li, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940404/
https://www.ncbi.nlm.nih.gov/pubmed/36805818
http://dx.doi.org/10.1186/s13229-023-00540-x

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