Enhanced antitumor activity of a novel, oral, helper epitope-containing WT1 protein vaccine in a model of murine leukemia

BACKGROUND: A Wilms’ tumor 1 (WT1) oral vaccine, Bifidobacterium longum (B. longum) 420, in which the bacterium is used as a vector for WT1 protein, triggers immune responses through cellular immunity consisting of cytotoxic T lymphocytes (CTLs) and other immunocompetent cells (e.g., helper T cells)...

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Detalles Bibliográficos
Autores principales: Minagawa, Hikaru, Hashii, Yoshiko, Nakajima, Hiroko, Fujiki, Fumihiro, Morimoto, Soyoko, Nakata, Jun, Shirakawa, Toshiro, Katayama, Takane, Tsuboi, Akihiro, Ozono, Keiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940413/
https://www.ncbi.nlm.nih.gov/pubmed/36803483
http://dx.doi.org/10.1186/s12885-023-10547-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940413/
https://www.ncbi.nlm.nih.gov/pubmed/36803483
http://dx.doi.org/10.1186/s12885-023-10547-5

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