Incorporation of SARS-CoV-2 spike NTD to RBD protein vaccine improves immunity against viral variants

Emerging SARS-CoV-2 variants pose a threat to human health worldwide. SARS-CoV-2 receptor binding domain (RBD)-based vaccines are suitable candidates for booster vaccines, eliciting a focused antibody response enriched for virus neutralizing activity. Although RBD proteins are manufactured easily, a...

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Detalles Bibliográficos
Autores principales: Montgomerie, Isabelle, Bird, Thomas W., Palmer, Olga R., Mason, Ngarangi C., Pankhurst, Theresa E., Lawley, Blair, Hernández, Leonor C., Harfoot, Rhodri, Authier-Hall, Astrid, Anderson, Danielle E., Hilligan, Kerry L., Buick, Kaitlin H., Mbenza, Naasson M., Mittelstädt, Gerd, Maxwell, Samara, Sinha, Shubhra, Kuang, Joanna, Subbarao, Kanta, Parker, Emily J., Sher, Alan, Hermans, Ian F., Ussher, James E., Quiñones-Mateu, Miguel E., Comoletti, Davide, Connor, Lisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940465/
https://www.ncbi.nlm.nih.gov/pubmed/36845030
http://dx.doi.org/10.1016/j.isci.2023.106256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940465/
https://www.ncbi.nlm.nih.gov/pubmed/36845030
http://dx.doi.org/10.1016/j.isci.2023.106256

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