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Incorporation of SARS-CoV-2 spike NTD to RBD protein vaccine improves immunity against viral variants
Emerging SARS-CoV-2 variants pose a threat to human health worldwide. SARS-CoV-2 receptor binding domain (RBD)-based vaccines are suitable candidates for booster vaccines, eliciting a focused antibody response enriched for virus neutralizing activity. Although RBD proteins are manufactured easily, a...
Autores principales: | Montgomerie, Isabelle, Bird, Thomas W., Palmer, Olga R., Mason, Ngarangi C., Pankhurst, Theresa E., Lawley, Blair, Hernández, Leonor C., Harfoot, Rhodri, Authier-Hall, Astrid, Anderson, Danielle E., Hilligan, Kerry L., Buick, Kaitlin H., Mbenza, Naasson M., Mittelstädt, Gerd, Maxwell, Samara, Sinha, Shubhra, Kuang, Joanna, Subbarao, Kanta, Parker, Emily J., Sher, Alan, Hermans, Ian F., Ussher, James E., Quiñones-Mateu, Miguel E., Comoletti, Davide, Connor, Lisa M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940465/ https://www.ncbi.nlm.nih.gov/pubmed/36845030 http://dx.doi.org/10.1016/j.isci.2023.106256 |
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