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Empagliflozin suppresses mitochondrial reactive oxygen species generation and mitigates the inducibility of atrial fibrillation in diabetic rats
INTRODUCTION: Recent studies have demonstrated that sodium-glucose co-transporter-2 inhibitors (SGLT2-i) reduce the risk of atrial fibrillation (AF) in patients with diabetes mellitus (DM), in which oxidative stress due to increased reactive oxygen species (ROS) contributes to the pathogenesis of AF...
Autores principales: | Koizumi, Takuya, Watanabe, Masaya, Yokota, Takashi, Tsuda, Masumi, Handa, Haruka, Koya, Jiro, Nishino, Kotaro, Tatsuta, Daishiro, Natsui, Hiroyuki, Kadosaka, Takahide, Koya, Taro, Nakao, Motoki, Hagiwara, Hikaru, Kamada, Rui, Temma, Taro, Tanaka, Shinya, Anzai, Toshihisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940756/ https://www.ncbi.nlm.nih.gov/pubmed/36815024 http://dx.doi.org/10.3389/fcvm.2023.1005408 |
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