First-in-Class Dual Hybrid Carbonic Anhydrase Inhibitors and Transient Receptor Potential Vanilloid 1 Agonists Revert Oxaliplatin-Induced Neuropathy

[Image: see text] Here, we report for the first time a series of compounds potentially useful for the management of oxaliplatin-induced neuropathy (OINP) able to modulate the human Carbonic Anhydrases (hCAs) as well as the Transient Receptor Potential Vanilloid 1 (TRPV1). All compounds showed effect...

Descripción completa

Detalles Bibliográficos
Autores principales: Angeli, Andrea, Micheli, Laura, Carta, Fabrizio, Ferraroni, Marta, Pirali, Tracey, Fernandez Carvajal, Asia, Ferrer Montiel, Antonio, Di Cesare Mannelli, Lorenzo, Ghelardini, Carla, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940855/
https://www.ncbi.nlm.nih.gov/pubmed/36626645
http://dx.doi.org/10.1021/acs.jmedchem.2c01911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940855/
https://www.ncbi.nlm.nih.gov/pubmed/36626645
http://dx.doi.org/10.1021/acs.jmedchem.2c01911

Ejemplares similares