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CriSNPr, a single interface for the curated and de novo design of gRNAs for CRISPR diagnostics using diverse Cas systems

CRISPR-based diagnostics (CRISPRDx) have improved clinical decision-making, especially during the COVID-19 pandemic, by detecting nucleic acids and identifying variants. This has been accelerated by the discovery of new and engineered CRISPR effectors, which have expanded the portfolio of diagnostic...

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Detalles Bibliográficos
Autores principales: Ansari, Asgar H, Kumar, Manoj, Sarkar, Sajal, Maiti, Souvik, Chakraborty, Debojyoti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940907/
https://www.ncbi.nlm.nih.gov/pubmed/36752591
http://dx.doi.org/10.7554/eLife.77976