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Differential regulation of H3K9/H3K14 acetylation by small molecules drives neuron-fate-induction of glioma cell
Differentiation therapy using small molecules is a promising strategy for improving the prognosis of glioblastoma (GBM). Histone acetylation plays an important role in cell fate determination. Nevertheless, whether histone acetylation in specific sites determines GBM cells fate remains to be explore...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941105/ https://www.ncbi.nlm.nih.gov/pubmed/36805688 http://dx.doi.org/10.1038/s41419-023-05611-8 |