Differential regulation of H3K9/H3K14 acetylation by small molecules drives neuron-fate-induction of glioma cell

Differentiation therapy using small molecules is a promising strategy for improving the prognosis of glioblastoma (GBM). Histone acetylation plays an important role in cell fate determination. Nevertheless, whether histone acetylation in specific sites determines GBM cells fate remains to be explore...

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Detalles Bibliográficos
Autores principales: Liu, Xincheng, Guo, Cui, Leng, Tiandong, Fan, Zhen, Mai, Jialuo, Chen, Jiehong, Xu, Jinhai, Li, Qianyi, Jiang, Bin, Sai, Ke, Yang, Wenzhuo, Gu, Jiayu, Wang, Jingyi, Sun, Shuxin, Chen, Zhijie, Zhong, Yingqian, Liang, Xuanming, Chen, Chaoxin, Cai, Jing, Lin, Yuan, Liang, Jiankai, Hu, Jun, Yan, Guangmei, Zhu, Wenbo, Yin, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941105/
https://www.ncbi.nlm.nih.gov/pubmed/36805688
http://dx.doi.org/10.1038/s41419-023-05611-8

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