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The necessity of incorporating non-genetic risk factors into polygenic risk score models

The growing public interest in genetic risk scores for various health conditions can be harnessed to inspire preventive health action. However, current commercially available genetic risk scores can be deceiving as they do not consider other, easily attainable risk factors, such as sex, BMI, age, sm...

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Detalles Bibliográficos
Autores principales: van Dam, Sipko, Folkertsma, Pytrik, Castela Forte, Jose, de Vries, Dylan H., Herrera Cunillera, Camila, Gannamani, Rahul, Wolffenbuttel, Bruce H. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941118/
https://www.ncbi.nlm.nih.gov/pubmed/36807592
http://dx.doi.org/10.1038/s41598-023-27637-w