Endogenous DAF-16 spatiotemporal activity quantitatively predicts lifespan extension induced by dietary restriction

In many organisms, dietary restriction (DR) leads to lifespan extension through the activation of cell protection and pro-longevity gene expression programs. In the nematode C. elegans, the DAF-16 transcription factor is a key aging regulator that governs the Insulin/IGF-1 signaling pathway and unde...

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Detalles Bibliográficos
Autores principales: Huayta, Javier, Crapster, Joseph P., San-Miguel, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941123/
https://www.ncbi.nlm.nih.gov/pubmed/36807646
http://dx.doi.org/10.1038/s42003-023-04562-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941123/
https://www.ncbi.nlm.nih.gov/pubmed/36807646
http://dx.doi.org/10.1038/s42003-023-04562-2

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