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Endogenous DAF-16 spatiotemporal activity quantitatively predicts lifespan extension induced by dietary restriction
In many organisms, dietary restriction (DR) leads to lifespan extension through the activation of cell protection and pro-longevity gene expression programs. In the nematode C. elegans, the DAF-16 transcription factor is a key aging regulator that governs the Insulin/IGF-1 signaling pathway and unde...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941123/ https://www.ncbi.nlm.nih.gov/pubmed/36807646 http://dx.doi.org/10.1038/s42003-023-04562-2 |