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Structure-free antibody paratope similarity prediction for in silico epitope binning via protein language models
Antibodies are an important group of biological molecules that are used as therapeutics and diagnostic tools. Although millions of antibody sequences are available, identifying their structural and functional similarity and their antigen binding sites remains a challenge at large scale. Here, we pre...
Autores principales: | Ghanbarpour, Ahmadreza, Jiang, Min, Foster, Denisa, Chai, Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941125/ https://www.ncbi.nlm.nih.gov/pubmed/36824280 http://dx.doi.org/10.1016/j.isci.2023.106036 |
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