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Genomic evidence for adaptation to tuberculosis in the Andes before European contact

Most studies focusing on human high-altitude adaptation in the Andean highlands have thus far been focused on Peruvian populations. We present high-coverage whole genomes from Indigenous people living in the Ecuadorian highlands and perform multi-method scans to detect positive natural selection. We...

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Detalles Bibliográficos
Autores principales: Joseph, Sophie K., Migliore, Nicola Rambaldi, Olivieri, Anna, Torroni, Antonio, Owings, Amanda C., DeGiorgio, Michael, Ordóñez, Wladimir Galarza, Aguilú, J.J. Ortiz, González-Andrade, Fabricio, Achilli, Alessandro, Lindo, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941198/
https://www.ncbi.nlm.nih.gov/pubmed/36824277
http://dx.doi.org/10.1016/j.isci.2023.106034