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Genomic evidence for adaptation to tuberculosis in the Andes before European contact
Most studies focusing on human high-altitude adaptation in the Andean highlands have thus far been focused on Peruvian populations. We present high-coverage whole genomes from Indigenous people living in the Ecuadorian highlands and perform multi-method scans to detect positive natural selection. We...
Autores principales: | Joseph, Sophie K., Migliore, Nicola Rambaldi, Olivieri, Anna, Torroni, Antonio, Owings, Amanda C., DeGiorgio, Michael, Ordóñez, Wladimir Galarza, Aguilú, J.J. Ortiz, González-Andrade, Fabricio, Achilli, Alessandro, Lindo, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941198/ https://www.ncbi.nlm.nih.gov/pubmed/36824277 http://dx.doi.org/10.1016/j.isci.2023.106034 |
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