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A reversible mutation in a genomic hotspot saves bacterial swarms from extinction

Microbial adaptation to changing environmental conditions is frequently mediated by hypermutable sequences. Here we demonstrate that such a hypermutable hotspot within a gene encoding a flagellar unit of Paenibacillus glucanolyticus generated spontaneous non-swarming mutants with increased stress re...

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Detalles Bibliográficos
Autores principales: Hefetz, Idan, Israeli, Ofir, Bilinsky, Gal, Plaschkes, Inbar, Hazkani-Covo, Einat, Hayouka, Zvi, Lampert, Adam, Helman, Yael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941203/
https://www.ncbi.nlm.nih.gov/pubmed/36824284
http://dx.doi.org/10.1016/j.isci.2023.106043