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A quantitative evaluation of topological motifs and their coupling in gene circuit state distributions

One of the major challenges in biology is to understand how gene interactions collaborate to determine overall functions of biological systems. Here, we present a new computational framework that enables systematic, high-throughput, and quantitative evaluation of how small transcriptional regulatory...

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Detalles Bibliográficos
Autores principales: Clauss, Benjamin, Lu, Mingyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941213/
https://www.ncbi.nlm.nih.gov/pubmed/36824273
http://dx.doi.org/10.1016/j.isci.2023.106029