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Zika virus induced microcephaly and aberrant hematopoietic cell differentiation modeled in novel neonatal humanized mice

INTRODUCTION: Immunocompetent and immunocompromised murine models have been instrumental in answering important questions regarding ZIKV pathogenesis and vertical transmission. However, mimicking human congenital zika syndrome (CZS) characteristics in these murine models has been less than optimal a...

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Detalles Bibliográficos
Autores principales: Schmitt, Kimberly, Curlin, James Z., Remling-Mulder, Leila, Aboellail, Tawfik, Akkina, Ramesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941325/
https://www.ncbi.nlm.nih.gov/pubmed/36825016
http://dx.doi.org/10.3389/fimmu.2023.1060959