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A stay of execution: ATF4 regulation and potential outcomes for the integrated stress response

ATF4 is a cellular stress induced bZIP transcription factor that is a hallmark effector of the integrated stress response. The integrated stress response is triggered by phosphorylation of the alpha subunit of the eukaryotic initiation factor 2 complex that can be carried out by the cellular stress...

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Detalles Bibliográficos
Autores principales: Neill, Graham, Masson, Glenn R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941348/
https://www.ncbi.nlm.nih.gov/pubmed/36825279
http://dx.doi.org/10.3389/fnmol.2023.1112253